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The Cow Diversity Project: introducing undergraduates to molecular population genetics

This is a multi-week laboratory exercise that involves sequencing a pair of mitochondrial genes in cows. Using data from several samples, students calculate diversity (variation within species) and divergence (variation between species). The exercise reinforces principles in molecular genetics (DNA purification, PCR, etc.) and introduces principles in molecular population genetics. We provide an overview of the project, detailed notes for instructors, and the handout we currently use.
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Primary or BEN resource type
General Biology Core Concepts
Discipline Specific Core Concepts
Life science discipline (subject)
Keywords divergence, diversity, DNA sequencing
Key taxa Bos taurus, Bison bison
Intended End User Role
Educational Language
Pedagogical Use Description This exercise requires numerous molecular biology methods, ultimately leading students to quantitative analysis of DNA sequence variation
Primary Author Controlled Name
Primary Author Affiliation Cedar Crest College
Primary Author email
Secondary Author Name(s) Andre Walther, Debra Walther
Secondary Author Affiliation(s) Cedar Crest College, Muhlenberg College
Secondary Author Email(s),
Submitter Name Richard Kliman
Submitter Email
Rights Richard Kliman
Date Of Record Submission 2016-05-21

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